Product Name

Phospho-Tau (Ser404) Rabbit pAb

Gene ID

4137

SwissProt ID

P10636

Gene Name

MAPT

Alternative Names

MAPT; MAPTL; MTBT1; TAU; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type.

Research Field

Neuroscience

Product Categories

Primary antibody

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-P,ICC/IF

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

Molecular Weight

Calculated MW: 79 kDa; Observed MW: 48,62,78 kDa

Clonality

Polyclonal Antibody

Clonality No.

-

Isotype

IgG

Immunogen

Synthetic peptide of human MAPT

Purification

Affinity Purified

Conjugation

Unconjugated

Modification

Phosphorylated

Form

Liquid

Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Western blot analysis of Phospho-Tau (Ser404) in C6 lysates using Phospho-Tau (Ser404) antibody.

Immunohistochemistry analysis of paraffin-embedded rat hippocampal region tissue from a model with Alzheimer using Phospho-Tau (Ser404) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence analysis of Phospho-Tau (Ser404) in Hela using Tau(Phospho-Ser404) antibody(red).