抗体
试剂盒
多肽
探针
蛋白
组织芯片
产品中心
Product Center
ERK1/2 mouse monoclonal antibody
All
TD-AB0023
- Catalog： TD-AB0023
- Clonality： mAb
- Application： WB
- Synonyms： ERK; ERT1; MAPK1/2
-
规格：
100ug
-
价格：
¥2000
定制服务咨询
ERK1/2 mouse monoclonal antibody
| Product Name | ERK1/2 mouse monoclonal antibody |
| Cat.# | TD-AB0023 |
| Package | 25 μl/100 μl/200 μl |
| Storage | PBS with 0.1% sodium azide and 50% glycerol, pH 7.2 |
| Product Imformation | |
| Description | Anti-ERK1/2 Monoclonal A |
| Applications | WB |
| Immunogen | A synthetic peptide coupled |
| Reactivity | Human Mouse Rat |
| Host species | Mouse |
| Ig class | IgG1 |
| Purity | Protein A/G Affinity Purification |
| Target information | |
| Symbol | |
| Synonyms | ERK; ERT1; MAPK1/2 |
| Target Background | |
| ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways. When growth factors bind to the receptor tyrosine kinase, Ras interacts with Raf, the serine /threonine protein kinase and activates it as well. Once actived, Raf phosphorylates serine residue in 2 further kinases, MEK1/2, which in turn phosphorylates tyrosine/threonine in extracellular-signal regulated kinase (ERK) 1/2. Upon activation, the ERKs either phosphorylate a number of cytoplasmic targets or migrate to the nucleus, where they phosphorylate and activate a number of transcription factors such as c-Fos and Elk-1. | |
| Western blotting | |
| Predicted band size | 44/42kDa |
| Positive control | Recombinant human ERK1 protein |
| Recommended dilution | 1:1,000-2,000 |
| Product Image | |
| |
|