TD-VK632016

Foravirumab(TD-VK632016) is a research-grade recombinant antibody targetingG/Glycoprotein. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.

Rabies virus (RABV)

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Human

IgG1, kappa

Monoclonal

G/Glycoprotein

Please contact the lab for this information.

>95% purity as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

O92284

Liquid

0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

CR4098, 944548-38-3

Foravirumab (CR4098), is currently under phase II clinical trial in the form of a cocktail with rafivirumab (CR57), a mAb derived from somatic cell hybridization targeting rabies virus glycoprotein antigenic site I.• Structure and function of respiratory syncytial virus surface glycoproteins., PMID:24362685• Full-length G glycoprotein directly extracted from rabies virus with detergent and then stabilized by amphipols in liquid and freeze-dried forms., PMID:34297405• Recombinant Soluble Henipavirus Glycoprotein Preparation., PMID:37610572• Ephedrae Herba and Cinnamomi Cortex interactions with G glycoprotein inhibit respiratory syncytial virus infectivity., PMID:35079103• VSV-G Viral Envelope Glycoprotein Prepared fromPichia pastorisEnhances Transfection of DNA into Animal Cells., PMID:28297751• Spatiotemporal transcriptomic mapping of regenerative inflammation in skeletal muscle reveals a dynamic multilayered tissue architecture., PMID:39190487• Vesicular Stomatitis Virus (VSV) G Glycoprotein Can Be Modified to Create a Her2/Neu-Targeted VSV That Eliminates Large Implanted Mammary Tumors., PMID:37199666• Evolutionary trends of respiratory syncytial viruses: Insights from large-scale surveillance and molecular dynamics of G glycoprotein., PMID:38784562• G glycoprotein amino acid residues required for human monoclonal antibody RAB1 neutralization are conserved in rabies virus street isolates., PMID:21693135• The use of monoclonal antibodies and lectins to identify changes in viral glycoproteins that are influenced by glycosylation: the case of human respiratory syncytial virus attachment (G) glycoprotein., PMID:17502674

SEC-HPLC detection for Research Grade Foravirumab.　　|　Detects Human G/Glycoprotein in indirect ELISAs.　　|　SDS-PAGE for Research Grade Foravirumab.

For research use only. Not suitable for clinical or therapeutic use.