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Research Grade Diridavumab
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TD-VK515016_1.jpg
TD-VK515016_2.jpg
- Catalog： TD-VK515016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： CR-6261,CR6261,CAS:1393659-46-5
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规格：
1mg
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价格：
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Research Grade Diridavumab
| Catalog No. | TD-VK515016 |
|---|---|
| Description | Diridavumab, the alternative name, CR6261, is a human monoclonal antibody directed against influenza A hemagglutinin. The CR6261 antibody was first discovered by the Scripps Institute and Crucell, a Dutch biopharmaceutical company, and later developed by Janssen Pharmaceutical Companies of Johnson & Johnson under the trade name diridavumab. Cr6261 is under investigation in clinical trial NCT02016066 (A Study to Assess the Safety, Pharmacokinetics and Immunogenicity of Diridavumab in Japanese Healthy Participants). |
| Species reactivity | Influenza A virus |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG1, lambda |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | HA/Hemagglutinin |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P03455 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | CR-6261,CR6261,CAS:1393659-46-5 |
| Background | Diridavumab is a monoclonal anti-HA stalk antibody. Diridavumab stabilizes the prefusion HA structure and prevents pH-dependent fusion of cellular and viral membranes in endosomes. Diridavumab can be used in research of H2 influenza virus. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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SEC-HPLC detection for Research Grade Diridavumab. |
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SDS-PAGE for Research Grade Diridavumab. |