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Research Grade Gantenerumab
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- Catalog： TD-HY235036
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： R1450,CAS:1043556-46-2
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规格：
1mg
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价格：
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Research Grade Gantenerumab
| Catalog No. | TD-HY235036 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG1-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | AICD-57, A4, Beta-CTF, Protease nexin-II, Gamma-CTF(50), ABPP, S-APP-beta, APP, Abeta40, Abeta42, AID(59), Amyloid intracellular domain 59, AID(57), S-APP-alpha, Gamma-CTF(59), Beta-secretase C-terminal fragment, Amyloid-beta precursor protein, Amyloid precursor protein, Beta-APP42, PreA4, Alzheimer disease amyloid protein, APPI, PN-II, AICD-59, Alpha-secretase C-terminal fragment, Amyloid-beta A4 protein, Amyloid intracellular domain 57, CVAP, Amyloid intracellular domain 50, Beta-APP40, AD1, Cerebral vascular amyloid peptide, AID(50), Alpha-CTF, Gamma-CTF(57), AICD-50 |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P05067 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | R1450,CAS:1043556-46-2 |
| Background | Gantenerumab is a fully human anti-amyloid-β (Aβ) IgG1 monoclonal antibody demonstrates sustained cerebral amyloid-β binding. Gantenerumab can be used for Alzheimer's disease research. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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SEC-HPLC detection for Research Grade Gantenerumab. |
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SDS-PAGE for Research Grade Gantenerumab. |
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Flow-cytometry using anti-human APP antibody. SH-SY5Y cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human APP monoclonal antibody (Catalog TD-HY235036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (TD-HF690414) and cells analysed on a NovoCyte Flow Cytometer. |