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IL-17 Receptor C Rabbit pAb
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IL-17 Receptor C Rabbit pAb
| Product Name | IL-17 Receptor C Rabbit pAb |
| Gene ID | 84818 |
| SwissProt ID | Q8NAC3 |
| Gene Name | IL17RC |
| Alternative Names | IL17RC; Interleukin-17 receptor C; IL-17 receptor C; IL-17RC; Interleukin-17 receptor homolog; IL17Rhom; Interleukin-17 receptor-like protein; IL-17RL; ZcytoR14 |
| Background | This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. |
| Research Field | Immunology |
| Product Categories | Primary antibody |
| Host | Rabbit |
| Reactivity | Human |
| Application | IHC-P |
| Dilution Ratio | IHC: 1/50-1/100 |
| Molecular Weight | - |
| Clonality | Polyclonal Antibody |
| Clonality No. | - |
| Isotype | IgG |
| Immunogen | Fusion protein of human IL17RC |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Form | Liquid |
| Buffer System | pH 7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Immunohistochemistry analysis of paraffin-embedded Human tosil using IL-17 Receptor C antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |