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IL-3 Receptor alpha Mouse mAb
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IL-3 Receptor alpha Mouse mAb
| Product Name | IL-3 Receptor alpha Mouse mAb |
| Gene ID | 3563 |
| SwissProt ID | P26951 |
| Gene Name | IL3RA |
| Alternative Names | IL3RA; IL3R; Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; CD123 |
| Background | The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. |
| Research Field | Immunology |
| Product Categories | Primary antibody |
| Host | Mouse |
| Reactivity | Human |
| Application | ICC/IF,FC |
| Dilution Ratio | IF: 1/50-1/200 FC: 1/50-1/100 |
| Molecular Weight | - |
| Clonality | Monoclonal Antibody |
| Clonality No. | 7B2 |
| Isotype | IgG1 |
| Immunogen | Purified recombinant fragment of human IL3RA expressed in E. Coli. |
| Purification | Ascitic Fluid |
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Form | Liquid |
| Buffer System | Ascitic fluid containing 0.03% sodium azide. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Flow Cytometry analysis of Hela cells stained with IL-3RA antibody (green) and negative control (red). |
Flow Cytometry analysis of Hela cells stained with IL-3RA antibody (green) and negative control (red). |