| Catalog No. |
TD-RP11278 |
| Synonyms |
Diabetes-Associated Peptide (DAP), amide, human; Insulinoma or islet amyloid polypeptide (IAPP) |
| Description |
Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin resistance of type II diabetes mellitus through its modulation of peripheral effects of insulin. Amylin blocks the activation of glycogen synthase by insulin. |
| Cas No |
122384-88-7 |
| Sequence |
{LYS}{CYS}{ASN}{THR}{ALA}{THR}{CYS}{ALA}{THR}{GLN}{ARG}{LEU}{ALA}{ASN}{PHE}{LEU}{VAL}{HIS}{SER}{SER}{ASN}{ASN}{PHE}{GLY}{ALA}{ILE}{LEU}{SER}{SER}{THR}{ASN}{VAL}{GLY}{SER}{ASN}{THR}{TYR} |
| Sequence Shortening |
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY |
| Molecular Formula |
C₁₆₅H₂₆₁N₅₁O₅₅S₂ |
| C Terminal |
Amidation |
| Disulfide Bridge |
2-7 |
| Molecular Weight |
3903.28 |
| Purity |
> 95% |
| Solubility |
Soluble in Ultrapure water under 1mg/ml |
| Form |
Lyophilized |
| Storage |
Store at -20°C. Keep container tightly closed. Store in a cool dry place. |