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Anti-STK11 Mouse Monoclonal Antibody
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TD-26158
- Catalog： TD-26158
- Clonality： mAb
- Application： ELISA, WB, IHC
- Synonyms： STK11 Antibody
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规格：
100ul
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价格：
¥4800
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Anti-STK11 Mouse Monoclonal Antibody
| Cat. #: TD-26158 | |
| Size: 100 µL | |
| Gene Symbol: STK11, LKB1, PJS, hLKB1 | |
| Description: Anti-STK11 Mouse Monoclonal Antibody | |
| Background: Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response, and functions as a tumour suppressor. Recent studies have uncovered a large number of somatic mutations of the STK11 gene that are present in lung, cervical, breast, intestinal, testicular, pancreatic and skin cancer. | |
| Immunogen: A synthetic peptide from the internal region of STK, which includes the mutation of P281L, human origin. | |
| Applications: ELISA, WB, IHC | |
| Recommended Dilutions: ELISA: 1:1000-1:5000、WB: 1:100-1:1000、IHC: 1:50-1:200 | |
| Concentration: 0.5 mg/ml | |
| Host Species: Mouse | |
| Format: Liquid | |
| Clonality: Monoclonal | |
| Isotype: IgG | |
| Purity: Purified from ascites | |
| Preservative: No | |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol | |
| Species Reactivity: Recognizes P281L mutated, but not wild type STK11 of vertebrates. | |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing | |
| Immunofluorescence:
|
Immunofluorescence of cells expressing STK11 proteins with Anti-STK11 (P281L) antibody. HEK293T cells were transfected with pCDNA3-GFP-STK11 (WT) plasmid (left column) or pCDNA3-GFP-STK11 (P281L) plasmid (right column), then fixed and stained with Anti-STK11 (P281L) monoclonal antibody (Cat. #TD-26158). |