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CD338
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ELISA
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FCM
- Catalog： TD-32050
- Clonality： mAb
- Application： WB, IHC, IF, FCM
- Synonyms： MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; ABCG2; GOUT1; MXR-1; CDw338; UAQTL1; EST157481
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD338
| Description | |
| The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. |
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| Specification | |
| Aliases | MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; ABCG2; GOUT1; MXR-1; CDw338; UAQTL1; EST157481 |
| Entrez GeneID | 9429 |
| Swissprot | Q9UNQ0 |
| clone | 4H3C10 |
| WB Predicted band size | 75kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Purified recombinant fragment of human CD338 (AA: extra mix) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| IF | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using CD338 mouse mAb against A549 (1), HePG2 (2), Hela (3), and NIH/3T3 (4) cell lysate.
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Immunofluorescence analysis of Hela cells using CD338 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of Hela cells using CD338 mouse mAb (green) and negative control (red).
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Flow cytometric analysis of HePG2 cells using CD338 mouse mAb (green) and negative control (red).
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