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Human NEFL Protein
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Human NEFL Protein
| Product Name | Human NEFL Protein |
| Cat.# | TD-P1013 |
| Size | 50ug |
| Protein Name | NEFL |
| Synonym | NFL; NF-L; NF68; |
| Uniprot No. | P07196 |
| Expression System | E. Coli |
| Compound Identity | NEFL(e3)-his |
| Full Length or Truncated | Truncated |
| Molecular Weight | 32kD |
| Form | freeze-dried powde |
| Storage | -80°C (as supplied) |
| Stability | ≥6 months |
| Purity | ≥85% estimated by SDS-PAGE |
| Supplied in | 1×PBS (pH 7.2) |
| Background | |
| Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. | |
| SDS-PAGE Validation | |
| 12 % SDS-PAGE | Lane Description |
|
|
Lane 1: Protein Marker Lane 2: NEFL(e3)-pET21(1:5 dilution) |