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Human TDP43 Protein
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Human TDP43 Protein
| Product Name | Human TDP43 Protein |
| Cat.# | TD-P1014 |
| Size | 50ug |
| Protein Name | TDP43 |
| Synonym | ALS10; TDP-43 |
| Uniprot No. | Q13148 |
| Expression System | E. Coli |
| Compound Identity | TDP43(e3)-his |
| Full Length or Truncated | Full length |
| Molecular Weight | 47.2kD |
| Form | freeze-dried powder |
| Storage | -80°C (as supplied) |
| Stability | ≥6 months |
| Purity | ≥85% estimated by SDS-PAGE |
| Supplied in | 1×PBS (pH 7.2) |
| Background | |
| HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008] | |
| SDS-PAGE Validation | |
| 12 % SDS-PAGE | Lane Description |
|
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Lane 1: Protein Marker Lane 2: TDP43(e3)-Pet21 |