Product Name |
NF-kB p65 mouse monoclonal antibody |
Cat.# |
TD-AB0026 |
Package |
25 μl/100 μl/200 μl |
Storage |
PBS with 0.1% sodium azide and 50% glycerol, pH 7.2 |
Product Imformation |
Description |
NF-kB p65 Monoclonal Antibody |
Applications |
WB |
Immunogen |
Recombinant Protein |
Reactivity |
Human, Mouse, Rat |
Host species |
Mouse |
Ig class |
IgG1 |
Purity |
Protein A/G Affinity Purification |
Target information |
Symbol |
|
Synonyms |
RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit |
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Target Background |
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for RELA |