Product Name |
PARP mouse monoclonal antibody |
Cat.# |
TD-AB0036 |
Package |
25 μl/100 μl/200 μl |
Storage |
PBS with 0.1% sodium azide and 50% glycerol, pH 7.2 |
Product Imformation |
Description |
Anti-PARP mouse monoclonal antibody |
Applications |
WB |
Immunogen |
Synthetic peptide of human PARP1 |
Reactivity |
Human |
Host species |
Mouse |
Ig class |
IgG1 |
Purity |
Protein A/G Affinity Purification |
Target information |
Symbol |
PARP1 |
Full name |
poly(ADP-ribose) polymerase 1 |
Synonyms |
PARP; PARS; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1; PolyPARP |
Target Background |
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
Western blotting |
Predicted band size |
113 kDa |
Positive control |
Jurkat, K562, Hela, Raji, THP-1 and SW620 cell lysates |
Recommended dilution |
500-2000 |
Gel |
6%SDS-PAGE |
Lysate |
20 μg |
Lane 1-6 |
Jurkat, K562, Hela, Raji, THP-1 and SW620 cell lysates |
Primary antibody |
D194942(PARP1 Antibody) at dilution 1/1000 |
Secondary antibody |
HRP-conjugated Goat anti mouse IgG at 1/10000 dilution |
Exposure time |
2 minutes |
Product Image |
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