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STAT3 mouse monoclonal antibody
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TD-AB0052
- Catalog： TD-AB0052
- Clonality： mAb
- Application： WB
- Synonyms： APRF; HIES; ADMIO; ADMIO1
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规格：
100ug
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价格：
¥2000
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STAT3 mouse monoclonal antibody
| Product Name | STAT3 mouse monoclonal antibody |
| Cat.# | TD-AB0052 |
| Package | 25 μl/100 μl/200 μl |
| Storage | PBS with 0.1% sodium azide and 50% glycerol, pH 7.0-7.4 |
| Product Imformation | |
| Description | Anti- STAT3 mouse monoclonal antibody |
| Applications | WB |
| Immunogen | Fusion protein of human STAT3 |
| Reactivity | Human ,Mouse |
| Host species | Mouse |
| Ig class | IgG2a |
| Purity | Protein A/G Affinity Purification |
| Target information | |
| Symbol | STAT3 |
| Full name | signal transducer and activator of transcription 3 |
| Synonyms | APRF; HIES; ADMIO; ADMIO1 |
| Target Background | |
| The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. | |
| Western blotting | |
| Predicted band size | 88 kDa |
| Positive control | Hela cell, Mouse brain tissue, NIH/3T3 cell, Raji cell, RAW264.7 cell lysates |
| Recommended dilution | 1000-5000 |
| Gel | 8%SDS-PAGE |
| Lysate | 40 μg |
| Lane 1-5 | Hela cell, Mouse brain tissue, NIH/3T3 cell, Raji cell, RAW264.7 cell lysates |
| Primary antibody | D191080(STAT3 Antibody) at dilution 1/1200 |
| Secondary antibody | Goat anti mouse IgG at 1/5000 dilution |
| Exposure time | 1 minute |
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