Product Name |
MICU1 mouse monoclonal antibody |
Cat.# |
TD-AB0097 |
Package |
25 μl/100 μl/200 μl |
Storage |
PBS with 0.1% sodium azide and 50% glycerol, pH 7.2 |
Product Imformation |
Description |
Anti- MICU1 mouse monoclonal antibody |
Applications |
WB |
Immunogen |
Fusion protein of human MICU1 |
Reactivity |
Human |
Host species |
Mouse |
Ig class |
|
Purity |
Protein A/G Affinity Purification |
Target information |
Symbol |
MICU1 |
Full name |
mitochondrial calcium uptake 1 |
Synonyms |
CALC; EFHA3; MPXPS; CBARA1; ara CALC |
Target Background |
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. |
Western blotting |
Predicted band size |
54 kDa |
Positive control |
A549, Hela, K562 and 231 cell lysates |
Recommended dilution |
1000-5000 |
Gel |
12%SDS-PAGE |
Lysate |
40 μg |
Lane 1-4 |
A549, Hela, K562 and 231 cell lysates |
Primary antibody |
D191077(MICU1 Antibody) at dilution 1/1200 |
Secondary antibody |
Goat anti mouse IgG at 1/5000 dilution |
Exposure time |
10 seconds |
Product Image |
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