TD-HY280010

Iv0077 is a human IgG1 monoclonal antibody targeting CCL2. It reduced tumor-associated macrophage infiltration, slowed tumor progression, and enhanced chemotherapy efficacy.

Human

ELISA, FCM, Neutralization

Human

IgG1, kappa

Iv0077

Monoclonal

HC11, MCP-1, MCP1, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, Small-inducible cytokine A2, SCYA2, MCAF, Monocyte secretory protein JE, C-C motif chemokine 2, Monocyte chemoattractant protein 1, CCL2

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

P13500

Liquid

0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

SEC-HPLC detection for InVivoMAb Anti-Human CCL2/MCP-1 (ABV0269).　　|　　Flow-cytometry using anti-human CCL2 antibody.A549 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CCL2 antibody monoclonal antibody (Catalog No.:TD-HY280010 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog No.:TD-HF690414) and cells analysed on a NovoCyte Flow Cytometer.,Flow-cytometry using anti-human CCL2 antibody.Human peripheral blood lymphocytes were stained with an irrelevant antibody (Blue Histogram) or an anti-human CCL2 antibody monoclonal antibody (Catalog No.:TD-HY280010 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog No.:TD-HF690414) and cells analysed on a NovoCyte Flow Cytometer.　　|　　SDS-PAGE for InVivoMAb Anti-Human CCL2/MCP-1 (Iv0077).　　|　　Western blot analysis was performed using anti-CCL2/MCP-1 monoclonal antibody at 1μg/ml on various samples.Lane 1:recombinant human CCL2/MCP-1 (Catalog No.:TD-HY280012), 50ngLane 2:recombinant human CCL2/MCP-1 (Catalog No.:TD-HY280012), 30ngLane 3:recombinant human CCL2/MCP-1 (Catalog No.:TD-HY280012), 20ngLane 4:recombinant human CCL2/MCP-1 (Catalog No.:TD-HY280012), 10ng

For research use only. Not suitable for clinical or therapeutic use.