Description
Iv0027 is a selective, humanized recombinant monoclonal antibody that targets interleukin-13 (IL-13). Iv0027 binds IL-13 with high affinity and potency, recognizing both the wild-type and common variant forms of the cytokine. By blocking IL-13’s interaction with its receptors IL-13Rα1 and IL-13Rα2, Iv0027 effectively inhibits downstream IL-13 signaling, making it a useful research tool for studying IL-13–driven pathways involved in type 2 inflammation, airway remodeling, and fibrotic processes.