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CD369
All
ELISA
IF
FCM
  • CatalogTD-31623
  • ClonalitymAb
  • Application FCM, IF
  • SynonymsCLEC7A; BGR; CANDF4; SCARE2; DECTIN1; CLECSF12
  • 规格
    100ul 50ul
  • 价格
    ¥2180
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Mouse Monoclonal Antibody to CD369


Description
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
 
Specification
Aliases CLEC7A; BGR; CANDF4; SCARE2; DECTIN1; CLECSF12
Entrez GeneID 64581
Swissprot Q9BXN2
clone 4G2G6
WB Predicted band size 27.6kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD369 (AA: extra 66-247) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
Product Image
TD-316231.jpg
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

TD-316233.jpg

Immunofluorescence analysis of Hela cells using CD369 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
TD-316232.jpg
Flow cytometric analysis of HL-60 cells using CD369 mouse mAb (green) and negative control (red).