This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
Specification
Aliases
FCRL3; FCRH3; IFGP3; IRTA3; SPAP2
Entrez GeneID
115352
Swissprot
Q96P31
clone
4B4B2
WB Predicted band size
80.9kDa
Host/Isotype
Mouse IgG2a
Antibody Type
Primary antibody
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD307C (AA: extra 18-153) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Application
WB
1/500 - 1/2000
FCM
1/200 - 1/400
ELISA
1/10000
Product Image
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Flow cytometric analysis of HL-60 cells using CD307C mouse mAb (green) and negative control (red).