This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Specification
Aliases
FCRL1; FCRH1; IFGP1; IRTA5
Entrez GeneID
115350
Swissprot
Q96LA6
clone
4E9B9
WB Predicted band size
47kDa
Host/Isotype
Mouse IgG1
Antibody Type
Primary antibody
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD307A (AA: extra 17-202) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Application
FCM
1/200 - 1/400
ELISA
1/10000
Product Image
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Flow cytometric analysis of HL-60 cells using CD307A mouse mAb (green) and negative control (red).