Cat.# |
TD-200922 |
Product Name
|
CD133 (6H10) Mouse mAb
|
Gene ID
|
8842
|
SwissProt ID
|
O43490
|
Gene Name
|
PROM1
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Alternative Names
|
Prominin-1; Antigen AC133; Prominin-like protein 1; CD133.
|
Background
|
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
|
Research Field
|
Neuroscience
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Product Categories
|
Primary antibody
|
Host
|
Mouse
|
Reactivity
|
Human
|
Application
|
WB
|
Dilution Ratio
|
WB: 1/500-1/1000
|
Molecular Weight
|
Calculated MW: 97 kDa; Obs/erved MW: 133 kDa
|
Clonality
|
Monoclonal Antibody
|
Clonality No.
|
6H10-F1-C11
|
Isotype
|
IgG2a
|
Immunogen
|
Purified recombinant human Prominin-1 protein fragments expressed in E.coli.
|
Purification
|
Affinity Purified
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Conjugation
|
Unconjugated
|
Modification
|
Unmodified
|
Form
|
Liquid
|
Buffer System
|
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
|
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
|