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CD86 Rabbit mAb
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- Catalog： TD-R380350
- Clonality： mAb
- Application： WB, IHC-P, ICC/IF, IP, FC
- Synonyms： CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86
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规格：
100ul 50ul 20ul
-
价格：
¥2280
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CD86 Rabbit mAb
| Cat.# | TD-R380350 |
|
Product Name
|
CD86 Rabbit mAb
|
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Gene ID
|
942
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SwissProt ID
|
P42081
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Gene Name
|
CD86
|
|
Alternative Names
|
CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86
|
|
Background
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Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
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Research Field
|
Immunology
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Product Categories
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Primary antibody
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Host
|
Rabbit
|
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Reactivity
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Human,Rat
|
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Application
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WB,IHC-P,ICC/IF,FC,IP
|
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Dilution Ratio
|
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
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Molecular Weight
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Calculated MW: 38 kDa; Obs/erved MW: 70 kDa
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|
Clonality
|
Monoclonal Antibody
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Clonality No.
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R04-2A6
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Isotype
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IgG
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Immunogen
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A synthesized peptide derived from human CD86
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Purification
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Affinity Chromatography
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Conjugation
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Unconjugated
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Modification
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Unmodified
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Form
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Liquid
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|
Buffer System
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Western blot analysis of CD86 in Daudi，C6 lysates using CD86 antibody. |
Western blot analysis of CD86 in Raji lysates using CD86 antibody. |
Immunohistochemistry analysis of paraffin-embedded Human tonsil using CD86 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |
|
Immunofluorescence analysis of CD86 in K562 using CD86 antibody. |