Cat.# |
TD-R381689 |
Product Name
|
CD74 Rabbit mAb
|
Gene ID
|
972
|
SwissProt ID
|
P04233
|
Gene Name
|
CD74
|
Alternative Names
|
CD74; DHLAG; HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33;
|
Background
|
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place.
|
Research Field
|
Immunology
|
Product Categories
|
Primary antibody
|
Host
|
Rabbit
|
Reactivity
|
Human
|
Application
|
WB,IHC-P,ICC/IF,FC
|
Dilution Ratio
|
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
|
Molecular Weight
|
Calculated MW: 34 kDa
|
Clonality
|
Monoclonal Antibody
|
Clonality No.
|
R09-8J3
|
Isotype
|
IgG
|
Immunogen
|
A synthesized peptide derived from human CD74
|
Purification
|
Affinity Chromatography
|
Conjugation
|
Unconjugated
|
Modification
|
Unmodified
|
Form
|
Liquid
|
Buffer System
|
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
Storage
|
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
|