Cat.# |
TD-R23848 |
Product Name
|
CD55 Rabbit mAb
|
Gene ID
|
1604
|
SwissProt ID
|
P08174
|
Gene Name
|
CD55
|
Alternative Names
|
CD55; CR; DAF; Complement decay-accelerating factor; CD55
|
Background
|
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
|
Research Field
|
Immunology
|
Product Categories
|
Primary antibody
|
Host
|
Rabbit
|
Reactivity
|
Human
|
Application
|
WB
|
Dilution Ratio
|
WB: 1/500-1/1000
|
Molecular Weight
|
Calculated MW: 41 kDa; Obs/erved MW: 78 kDa
|
Clonality
|
Monoclonal Antibody
|
Clonality No.
|
R01-7H4
|
Isotype
|
IgG
|
Immunogen
|
A synthetic peptide of human CD55
|
Purification
|
Affinity Purified
|
Conjugation
|
Unconjugated
|
Modification
|
Unmodified
|
Form
|
Liquid
|
Buffer System
|
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
|
Storage
|
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
|