Cat.# |
TD-R380755 |
Product Name
|
CD46 Rabbit mAb
|
Gene ID
|
4179
|
SwissProt ID
|
P15529
|
Gene Name
|
CD46
|
Alternative Names
|
MCP; MIC10; TLX; TRA2.10; CD46
|
Background
|
CD46 is a type I membrane protein and a regulatory part of the complement system. This protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, CD46 can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria.
|
Research Field
|
Immunology
|
Product Categories
|
Primary antibody
|
Host
|
Rabbit
|
Reactivity
|
Human
|
Application
|
WB,IHC-P,ICC/IF
|
Dilution Ratio
|
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
|
Molecular Weight
|
Calculated MW: 44 kDa; Obs/erved MW: 44 kDa
|
Clonality
|
Monoclonal Antibody
|
Clonality No.
|
R06-3I6
|
Isotype
|
IgG
|
Immunogen
|
A synthesized peptide derived from human CD46
|
Purification
|
Affinity Chromatography
|
Conjugation
|
Unconjugated
|
Modification
|
Unmodified
|
Form
|
Liquid
|
Buffer System
|
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
Storage
|
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
|