Cat.# |
TD-R23795 |
Product Name
|
CD22 Rabbit mAb
|
Gene ID
|
933
|
SwissProt ID
|
P20273
|
Gene Name
|
CD22
|
Alternative Names
|
CD22; SIGLEC2; B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14; CD antigen CD22
|
Background
|
Acts as a regulator of B cell signaling. CD22 is expressed as both a cytoplasmic and membrane protein during discrete stages of B cell lymphocyte differentiation. The cytoplasmic form of CD22, expressed early in B cell development, is a useful marker for acute lymphocytic leukemia. The membrane form of CD22 is expressed in mature B cells prior to their differentiation into plasma cells. Alternative splicing results in two different isoforms, CD22α and CD22β.
|
Research Field
|
Immunology
|
Product Categories
|
Primary antibody
|
Host
|
Rabbit
|
Reactivity
|
Human
|
Application
|
WB,ICC/IF,IP
|
Dilution Ratio
|
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
|
Molecular Weight
|
Calculated MW: 95 kDa; Obs/erved MW: 140 kDa
|
Clonality
|
Monoclonal Antibody
|
Clonality No.
|
R01-8D2
|
Isotype
|
IgG
|
Immunogen
|
Recombinant protein of human CD22
|
Purification
|
Affinity Purified
|
Conjugation
|
Unconjugated
|
Modification
|
Unmodified
|
Form
|
Liquid
|
Buffer System
|
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
|
Storage
|
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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