Cat.# |
TD-R380675 |
Product Name
|
CD11b Rabbit mAb
|
Gene ID
|
3684
|
SwissProt ID
|
P11215
|
Gene Name
|
ITGAM
|
Alternative Names
|
ITGAM; CD11B; CR3A; Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b
|
Background
|
ITGAM, also named as CD11B and CR3A, belongs to the integrin alpha chain family. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. ITGAM is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b.
|
Research Field
|
Signal Transduction
|
Product Categories
|
Primary antibody
|
Host
|
Rabbit
|
Reactivity
|
Human,Mouse,Rat
|
Application
|
WB,IHC-P,ICC/IF
|
Dilution Ratio
|
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
|
Molecular Weight
|
Calculated MW: 127 kDa; Obs/erved MW: 170 kDa
|
Clonality
|
Monoclonal Antibody
|
Clonality No.
|
R08-8K6
|
Isotype
|
IgG
|
Immunogen
|
A synthesized peptide derived from human CD11b
|
Purification
|
Affinity Chromatography
|
Conjugation
|
Unconjugated
|
Modification
|
Unmodified
|
Form
|
Liquid
|
Buffer System
|
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
Storage
|
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
|