Cat.# |
TD-R23808 |
Product Name
|
CD3 epsilon Rabbit mAb
|
Gene ID
|
916
|
SwissProt ID
|
P07766
|
Gene Name
|
CD3E
|
Alternative Names
|
CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e
|
Background
|
The CD3 complex mediates signal transduction. When T cells encounter antigens via the T cell receptor (TCR), information about the quantity and quality of antigens is relayed to the intracellular signal transduction machinery . This activation process depends mainly on CD3 (Cluster of Differentiation 3), a multiunit protein complex that directly associates with the TCR. CD3 is composed of four polypeptides: ζ, γ, ε and δ.
|
Research Field
|
Immunology
|
Product Categories
|
Primary antibody
|
Host
|
Rabbit
|
Reactivity
|
Human
|
Application
|
WB,IHC-P,IP
|
Dilution Ratio
|
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
|
Molecular Weight
|
Calculated MW: 23 kDa; Obs/erved MW: 23 kDa
|
Clonality
|
Monoclonal Antibody
|
Clonality No.
|
R02-1B5
|
Isotype
|
IgG
|
Immunogen
|
A synthetic peptide of human CD3 epsilon
|
Purification
|
Affinity Purified
|
Conjugation
|
Unconjugated
|
Modification
|
Unmodified
|
Form
|
Liquid
|
Buffer System
|
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
|
Storage
|
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
|