TD-YP862016

Bavituximab(TD-YP862016) is a research-grade recombinant antibody targetingPhosphatidylserine. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.

General

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Chimeric

IgG1-kappa

Monoclonal

Phosphatidylserine

Please contact the lab for this information.

>95% purity as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

1446756-47-3

Liquid

0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Tarvacinch3 G4, CAS: 648904-28-3

Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel and Carboplatin, have enhanced inhibition on non-small-cell lung cancer.• Phosphatidylserine and the human brain., PMID:25933483• The distribution and function of phosphatidylserine in cellular membranes., PMID:20192774• Phosphatidylserine transport in cell life and death., PMID:37413778• Phosphatidylserine., PMID:10541030• Phosphatidylserine: A Novel Target for Ischemic Stroke Treatment., PMID:39456225• Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis., PMID:33539192• Phosphatidylserine externalization as immune checkpoint in cancer., PMID:38573347• Phosphatidylserine: A comprehensive overview of synthesis, metabolism, and nutrition., PMID:39097133• Dynamics of phagocytosis mediated by phosphatidylserine., PMID:36281986• Flagging fusion: Phosphatidylserine signaling in cell-cell fusion., PMID:33581114

SEC-HPLC detection for Research Grade Bavituximab.　　|　SDS-PAGE for Research Grade Bavituximab

For research use only. Not suitable for clinical or therapeutic use.