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抗体药类似物
Research Grade Casirivimab
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  • CatalogTD-VK565046
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsREGN-10933,REGN10933,CAS:2415933-42-3
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Casirivimab


Catalog No. TD-VK565046
Species reactivity SARS-CoV-2 (2019-nCoV)
Applications Research Grade Biosimilar
Host species Human
Isotype IgG1, kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Spike glycoprotein, S glycoprotein, E2, Peplomer protein, Spike protein S1, Spike protein S2, Spike protein S2', S, 2
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P0DTC2
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names REGN-10933,REGN10933,CAS:2415933-42-3
Background Casirivimab (REGN10933) is a human monoclonal antibody that targets the SARS-CoV-2 virus, which causes COVID-19. Casirivimab is ineffective against COVID-19 variants. Casirivimab can be used in combination with Imdevimab (HY-P99342), which alters the lung response of K18-hACE2 mice to the SARS-CoV-2 δ variant, effectively reducing viral load and improving symptoms.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SEC-HPLC
 
SEC-HPLC detection for Research Grade Casirivimab.
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Bioactivity
 
Detects Recombinant SARS-CoV-2 Spike protein receptor binding domain (Cat No.:TD-VK565021) in indirect ELISA.
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SDS-PAGE
 
SDS-PAGE for Research Grade Casirivimab.