Iv0255 is an antibody that recognizes mouse CCR8, a chemokine receptor involved in recruiting and regulating immunosuppressive T cells in the tumor microenvironment. Iv0255 shows clear dose-dependent anti-tumor activity across multiple mouse models. In CD34 humanized mice, intravenous Iv0255 effectively inhibited the growth of HCC827 human lung cancer xenografts. In syngeneic models, intraperitoneal Iv0255 similarly suppressed tumor growth in both LLC lung cancer and H22 liver cancer. Higher doses consistently produced stronger tumor-volume inhibition.
Protein A/G purified from cell culture supernatant.
Accession
P56484
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Caption
SDS-PAGE for InVivoMAb Anti-Mouse CD198/CCR8 Antibody (Iv0255)
Note
For research use only. Not suitable for clinical or therapeutic use.
抗体
试剂盒
多肽
蛋白
组织芯片
定制服务咨询