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抗体药类似物
Research Grade Suvratoxumab
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  • CatalogTD-JN998026
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsMEDI4893,CAS:1629620-18-3
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Suvratoxumab


Catalog No. TD-JN998026
Species reactivity Staphylococcus aureus
Applications Research Grade Biosimilar
Host species Human
Isotype IgG1-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Alpha-hemolysin, hly, Alpha-HL, Alpha-toxin, hla
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P09616
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names MEDI4893,CAS:1629620-18-3
Background Suvratoxumab (MEDI4893) is a long-acting, high-affinity human anti-α-toxin monoclonal antibody (IgG1κ type). Suvratoxumab potently neutralizes α-toxin, a key S. aureus virulence factor. Suvratoxumab improves survival and reduces lung injury in an immunocompromised mice model of pneumonia. Suvratoxumab also enhances the antibacterial activity of Vancomycin (HY-B0671) or Linezolid (HY-10394).
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SEC-HPLC
 
SEC-HPLC detection for Research Grade Suvratoxumab.
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Bioactivity
 
Detects Alpha-toxin/hly in indirect ELISAs.
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SDS-PAGE
 
SDS-PAGE for Research Grade Suvratoxumab.