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Research Grade Tosatoxumab
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- Catalog： TD-JN998016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： KBSA301,CAS:1374419-41-6
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规格：
1mg
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价格：
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Research Grade Tosatoxumab
| Catalog No. | TD-JN998016 |
|---|---|
| Species reactivity | Staphylococcus aureus |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG1-lambda |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | Alpha-hemolysin, hly, Alpha-HL, Alpha-toxin, hla |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P09616 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | KBSA301,CAS:1374419-41-6 |
| Background | Tosatoxumab (AR-301; KBSA301) is a human immunoglobulin G1 monoclonal antibody that specifically neutralizes alpha-toxin (alpha-hemolysin; Hla) of S. aureus. Tosatoxumab binds to an N-terminal epitope of alpha-toxin, thereby preventing functional toxin pore oligomerisation. Tosatoxumab has the potential for passive immunotherapy in the S. aureus pneumonia as an adjunctive therapy to standard antibiotic agent. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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SEC-HPLC detection for Research Grade Tosatoxumab. |
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Detects Alpha-toxin/hly in indirect ELISAs. |
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SDS-PAGE for Research Grade Tosatoxumab. |