TD-JN961016

Omodenbamab(TD-IN961016) is a research-grade recombinant antibody targetingSpA. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.

Staphylococcus aureus

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Human

IgG3-Kappa

Monoclonal

SpA

Please contact the lab for this information.

>95% purity as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

P02976

Liquid

0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

514-G-3, 514-G3, PA8-G3, 2241724-48-9

Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection.• A comprehensive review on staphylococcal protein A (SpA): Its production and applications., PMID:30869160• Spa therapy and burn scar treatment: a systematic review of the literature., PMID:32875343• SpA plus IBD or IBD plus SpA: Does commutative property apply?, PMID:37678619• Seronegative spondyloarthropathy-associated inflammatory bowel disease., PMID:36688014• Spa Typing of Staphylococcus aureus Isolates., PMID:31523767• MRI for axial SpA: Diagnosis, disease activity assessment, and recent advances., PMID:38287559•spaTyping of Methicillin-Resistant Staphylococcus aureus Based on Whole-Genome Sequencing: the Impact of the Assembler., PMID:36350148• Trends in spa and balneology in postcovid era, outcomes, and perspectives., PMID:36868844• May spa therapy be a valid opportunity to treat hand osteoarthritis? A review of clinical trials and mechanisms of action., PMID:26156832• Distribution of the Most PrevalentSpaTypes among Clinical Isolates of Methicillin-Resistant and -SusceptibleStaphylococcus aureusaround the World: A Review., PMID:29487578

SDS-PAGE for Research Grade Omodenbamab

For research use only. Not suitable for clinical or therapeutic use.