EN
抗体药类似物
Research Grade Riliprubart
All
  • CatalogTD-HY598026
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsCAS:2756228-76-7
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Riliprubart


atalog No. TD-HY598026
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target C1 esterase, Complement C1s subcomponent, C1S, Complement component 1 subcomponent s
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P09871
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names CAS:2756228-76-7
Background Riliprubart (SAR445088) is an anti-C1s humanized monoclonal antibody that inhibits activated C1s in the proximal portion of the classical complement system. Riliprubart selectively inhibits activated C1s and prevents the enzymatic action of C1 on its substrates C4 and C2, thus inhibiting the formation of the classical pathway C3 convertase, C4b2a.
Note For research use only. Not for use in clinical or therapeutic applications.