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抗体药类似物
Research Grade Sarilumab
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  • CatalogTD-HY583016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsREGN88,SAR153191,CAS:1189541-98-7
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Sarilumab


Catalog No. TD-HY583016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG1-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target sIL6R, Interleukin-6 receptor subunit alpha, CD126, IL-6R 1, IL-6R subunit alpha, Membrane glycoprotein 80, gp80, IL6R, IL-6RA, IL-6 receptor subunit alpha, IL-6R-alpha
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P08887
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names REGN88,SAR153191,CAS:1189541-98-7
Background Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SEC-HPLC
 
SEC-HPLC detection for Research Grade Sarilumab.
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Bioactivity
 
Detects Human CD126/IL6R/IL-6RA in indirect ELISAs.
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SDS-PAGE
 
SDS-PAGE for Research Grade Sarilumab