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抗体药类似物
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Research Grade Cibisatamab
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Bioactivity
SDS-PAGE
  • Catalog： TD-HY546036
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： Bispecific, CEATCB, RG-7802, RO-6958688, 2101242-53-7
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HY546036
  • Description
    Cibisatamab(TD-HY546036) is a research-grade recombinant antibody targetingCD66. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Humanized
  • Isotype
    IgG1-kappa/lambdawithdomaincrossover
  • Clonality
    Monoclonal
  • Target
    Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    P06731 & P07766
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    Bispecific, CEATCB, RG-7802, RO-6958688, 2101242-53-7
  • Background
    Cibisatamab (CEA-TCB), a T cell bispecific antibody, binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab (CEA-TCB) triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. Cibisatamab (CEA-TCB) can be used for colorectal cancer research.
  • Caption
    Detects Human CD66e/CEA/CEACAM5 & CD3E separately in indirect ELISAs. ### Detects Human CD66e/CEA/CEACAM5 & CD3E separately in indirect ELISAs.　　|　SDS-PAGE for Research Grade Cibisatamab.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.