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Research Grade Cibisatamab
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- Catalog： TD-HY546036
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： Bispecific,CEATCB,RG-7802,RO-6958688,CAS:2101242-53-7
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规格：
1mg
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价格：
¥询价
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Research Grade Cibisatamab
| Catalog No. | TD-HY546036 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | IgG1-kappa/lambdawithdomaincrossover |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P06731 & P07766 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | Bispecific,CEATCB,RG-7802,RO-6958688,CAS:2101242-53-7 |
| Background | Cibisatamab (CEA-TCB), a T cell bispecific antibody, binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab (CEA-TCB) triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. Cibisatamab (CEA-TCB) can be used for colorectal cancer research. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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Detects Human CD66e/CEA/CEACAM5 & CD3E separately in indirect ELISAs. |
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Detects Human CD66e/CEA/CEACAM5 & CD3E separately in indirect ELISAs. |
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SDS-PAGE for Research Grade Cibisatamab. |