EN
抗体药类似物
Research Grade Eldelumab
All
TD-HY524016_1.jpg
TD-HY524016_2.jpg
  • CatalogTD-HY524016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsBMS-936557, MDX-1100, CAS: 946414-98-8
  • 规格
    1mg
  • 价格
    ¥询价
定制服务咨询

Research Grade Eldelumab


Catalog No. TD-HY524016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG1-kappa
Expression system Mammalian Cells
Species Human
Clonality Monoclonal
Target Gamma-IP10, C-X-C motif chemokine 10, INP10, 10 kDa interferon gamma-induced protein, Small-inducible cytokine B10, SCYB10, IP-10, CXCL10
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P02778
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate Names BMS-936557, MDX-1100, CAS: 946414-98-8
Background Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease.
Note For research use only. Not suitable for clinical or therapeutic use.

 

TD-HY524016_1.jpg
Bioactivity
 
Detects CXCL10/IP-10 in indirect ELISAs.
TD-HY524016_2.jpg
SDS-PAGE
 
SDS-PAGE for Research Grade Eldelumab.