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Research Grade Milatuzumab
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- Catalog： TD-HY465016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： CD74-DOX(ADC),MEDI-115,hLL1,hLL1-DOX(ADC),CAS:899796-83-9
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规格：
1mg
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价格：
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Research Grade Milatuzumab
| Catalog No. | TD-HY465016 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | IgG1-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | HLA-DR antigens-associated invariant chain, HLA class II histocompatibility antigen gamma chain, CD74, CLIP, Ia antigen-associated invariant chain, DHLAG, Ii |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P04233 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | CD74-DOX(ADC),MEDI-115,hLL1,hLL1-DOX(ADC),CAS:899796-83-9 |
| Background | Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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Detects CD74 in indirect ELISAs. |
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SDS-PAGE for Research Grade Milatuzumab. |