EN
抗体药类似物
Research Grade Volociximab
All
TD-HY464016_1.jpg
  • CatalogTD-HY464016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsCAS:558480-40-3
  • 规格
    1mg
  • 价格
    ¥询价
定制服务咨询

Research Grade Volociximab


Catalog No. TD-HY464016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Chimeric
Isotype IgG4-nd
Expression system Mammalian Cells
Clonality Monoclonal
Target CD49 antigen-like family member E, Integrin alpha-F, ITGA5, VLA-5, Fibronectin receptor subunit alpha, CD49e, Integrin alpha-5, FNRA
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P08648
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names CAS:558480-40-3
Background Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 (EC50=0.2 nM). Integrin α5β1 is a major fibronectin receptor involved in angiogenesis. Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs).
Note For research use only. Not for use in clinical or therapeutic applications.

 

TD-HY464016_1.jpg
SDS-PAGE
 
SDS-PAGE for Research Grade Volociximab.