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抗体药类似物
Research Grade Acazicolcept
All
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  • CatalogTD-HY422046
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsALPN-101,ICOSLvIgD-Fc,CAS:2270247-50-0
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Acazicolcept


Catalog No. TD-HY422046
Species reactivity Human
Applications Research Grade Biosimilar
Isotype Fusion - [ICOSLG N-terminal fragment (1-122)]2 - IGHG1 Fc (Fragment constant)
Expression system Mammalian Cells
Target CD28, TP44, T-cell-specific surface glycoprotein CD28, CD278, ICOS, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, AILIM
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P10747 & Q9Y6W8
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names ALPN-101,ICOSLvIgD-Fc,CAS:2270247-50-0
Background Acazicolcept (ALPN-101), an Fc fusion protein, is a dual inducible T cell costimulator (ICOS)/CD28 antagonist. Acazicolcept has anti-inflammatory activities.
Note For research use only. Not for use in clinical or therapeutic applications

 

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Bioactivity
 
Detects CD28 in indirect ELISAs.
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SDS-PAGE
 
SDS-PAGE for Research Grade Acazicolcept