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抗体药类似物
Research Grade Theralizumab
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  • CatalogTD-HY422026
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsTGN1412,TAB08,TAB-08,CD28-SuperMAB,CAS:906068-56-2
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Theralizumab


Catalog No. TD-HY422026
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG4
Expression system Mammalian Cells
Clonality Monoclonal
Target CD28, TP44, T-cell-specific surface glycoprotein CD28
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P10747
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names TGN1412,TAB08,TAB-08,CD28-SuperMAB,CAS:906068-56-2
Background Theralizumab (TGN1412) is a humanized lgG4 superagonistic anti-CD28 monoclonal antibody that directly stimulates T cells. Theralizumab can cause cytokine release syndrome (CRS). Theralizumab can be used for the research of rheumatoid arthritis.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 
Detects CD28 in indirect ELISAs.
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SDS-PAGE
 
SDS-PAGE for Research Grade Theralizumab.