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抗体药类似物
Research Grade Concizumab
All
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  • CatalogTD-HY403026
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsAnti-TFPI,NN7415,mab2021,CAS:1312299-39-0
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Concizumab


Catalog No. TD-HY403026
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG4-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Extrinsic pathway inhibitor, Lipoprotein-associated coagulation inhibitor, TFPI, EPI, LACI, TFPI1, Tissue factor pathway inhibitor
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P10646
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names Anti-TFPI,NN7415,mab2021,CAS:1312299-39-0
Background Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that binds to the Kunitz-type protease inhibitor (KPI) 2 structural domain of TFPI, thereby blocking the interaction of this structural domain with the FXa active site. Concizumab can be used in the study of haemophilia.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SDS-PAGE
 
SDS-PAGE for Research Grade Concizumab.
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SEC-HPLC
 
SEC-HPLC detection for Research Grade Concizumab.
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Bioactivity
 
Detects TFPI in indirect ELISAs.