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Research Grade Cixutumumab
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TD-HY353046_1.jpg
TD-HY353046_2.jpg
- Catalog： TD-HY353046
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： IMC-A12,LY3012217,CAS:947687-12-9
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规格：
1mg
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价格：
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Research Grade Cixutumumab
| Catalog No. | TD-HY353046 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG1-lambda |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | CD221, Insulin-like growth factor 1 receptor, IGF1R, Insulin-like growth factor I receptor, IGF-I receptor |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P08069 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | IMC-A12,LY3012217,CAS:947687-12-9 |
| Background | Cixutumumab (IMC-A12) is a human anti-IGF-1R monoclonal antibody with high affinity that inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of IGF-IR. Cixutumumab shows broad-spectrum anti-tumour activity and can be used in studies of cancers such as lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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Detects Human CD221/IGF1R in indirect ELISAs. |
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SDS-PAGE for Research Grade Cixutumumab. |