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Research Grade Sirukumab
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TD-HY328036_1.jpg
TD-HY328036_2.jpg
- Catalog： TD-HY328036
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： CNTO 136, CAS: 1194585-53-9
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规格：
1mg
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价格：
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Research Grade Sirukumab
| Catalog No. | TD-HY328036 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Human |
| Isotype | IgG1-kappa |
| Expression system | Mammalian Cells |
| Species | Human |
| Clonality | Monoclonal |
| Target | Hybridoma growth factor, BSF-2, IFN-beta-2, CDF, IL6, Interleukin-6, IL-6, B-cell stimulatory factor 2, Interferon beta-2, IFNB2, CTL differentiation factor |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P05231 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Alternate Names | CNTO 136, CAS: 1194585-53-9 |
| Background | Sirukumab (CNTO-136) is a humanized monoclonal anti-IL6 (Interleukin Related) IgG1κ antibody. Sirukumab binds to IL6, preventing IL6-mediated signal transduction and activation of transcriptional activators, thereby blocking the downstream biological effects of IL6. Sirukumab can be used in the study of active lupus nephritis and rheumatoid arthritis. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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Detects IL6 in indirect ELISAs. |
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SDS-PAGE for Research Grade Sirukumab. |