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Research Grade Fidasimtamab
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SDS-PAGE
  • Catalog： TD-HY286146
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： Bispecific, BH-2950, BH2950, IBI315, IBI-315, IBI3152377419-89-9
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HY286146
  • Description
    Fidasimtamab(TD-HY286146) is a research-grade recombinant antibody targetingCD340. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Humanized
  • Isotype
    IgG1-kappa
  • Clonality
    Monoclonal
  • Target
    p185erbB2, HER2, NGL, Tyrosine kinase-type cell surface receptor HER2, NEU, MLN 19, Proto-oncogene Neu, MLN19, ERBB2, Proto-oncogene c-ErbB-2, CD340, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    P04626 & Q15116
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    Bispecific, BH-2950, BH2950, IBI315, IBI-315, IBI3152377419-89-9
  • Background
    Fidasimtamab (IBI-315; BH2950) is a recombinant human IgG1 bispecific antibody that targets, binds and inhibits both HER2 and PD-1 and their downstream signalling pathways, and links PD-1 expressing T cells to HER2 expressing tumour cells. Fidasimtamab has potential immunosuppressive and antitumor activity.
  • Caption
    SDS-PAGE for Research Grade Fidasimtamab
  • Note
    For research use only. Not suitable for clinical or therapeutic use.