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抗体药类似物
Research Grade Margetuximab
All
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  • CatalogTD-HY286046
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsMGAH-22,CAS:1350624-75-7
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Margetuximab


Catalog No. TD-HY286046
Species reactivity Human
Applications Research Grade Biosimilar
Host species Chimeric
Isotype IgG1-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target p185erbB2, HER2, NGL, Tyrosine kinase-type cell surface receptor HER2, NEU, MLN 19, Proto-oncogene Neu, MLN19, ERBB2, Proto-oncogene c-ErbB-2, CD340, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P04626
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names MGAH-22,CAS:1350624-75-7
Background Margetuximab (MGAH22) is a chimeric anti-HER2 monoclonal antibody optimized Fc domain, with an EC50 value of 39.33 ng/mL. Margetuximab can be used for researching metastatic HER2-positive breast cancer.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SEC-HPLC
 
SEC-HPLC detection for Research Grade Margetuximab.
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Bioactivity
 
Detects CD340/ERBB2/HER2/NEU in indirect ELISAs.
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SDS-PAGE
 
SDS-PAGE for Research Grade Margetuximab.