EN
抗体药类似物
Research Grade Nofetumomab
All
  • CatalogTD-HY257206
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsTechnetiumTc99mnofetumomabmerpentan,CAS:165942-79-0
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Nofetumomab


Catalog No. TD-HY257206
Species reactivity Human
Applications Research Grade Biosimilar
Host species Mouse
Isotype Fab-G2b-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P11836
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names TechnetiumTc99mnofetumomabmerpentan,CAS:165942-79-0
Background Technetium (99mTc) nofetumomab merpentan (trade name Verluma) is a mouse monoclonal antibody derivative used in the diagnosis of lung cancer, gastrointestinal, breast, ovary, pancreas, kidney, cervix, and bladder carcinoma. The antibody part, nofetumomab, is attached to the chelator merpentan, which links it to the radioisotope technetium-99m (99mTc). Nofetumomab Nofetumomab is an antibody fragment that recognises the pancarcinoma glycoprotein antigen EpCAM. and/or CD20/MS4A1 It is the Fab part of murine MAb NR-LU-10. Merpentan The chelator part : merpentan is a phenthioate ligand, 2,3,5,6-tetrafluorophenyl-4,5-bis-5-[1-ethoxyethyl]-thioacetoamidopentanoate. Phenthioate Phenthioate is an insecticide (Cidial) = O,o-dimethyl-S-(carbethoxy-phenylmethyl)dithiophosphate
Note For research use only. Not for use in clinical or therapeutic applications.