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抗体药类似物
Research Grade Plamotamab
All
TD-HY257176_1.jpg
  • CatalogTD-HY257176
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsBispecific, XmAb-13676, CAS: 2138442-31-4
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Plamotamab


Catalog No. TD-HY257176
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG1-kappa/scFv-h-CH2-CH3
Expression system Mammalian Cells
Species Human
Clonality Monoclonal
Target B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P11836 & P07766
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate Names Bispecific, XmAb-13676, CAS: 2138442-31-4
Background Plamotamab (XmAb-13676) is a human bispecific antibody (bsAb) that binds CD3 and CD20. Plamotamab recruits cytotoxic T cells to kill CD20+ expressing tumor cells. Plamotamab induces a mild hematologic reaction (MR), and results in tumor regression in vivo.
Note For research use only. Not suitable for clinical or therapeutic use.

 

TD-HY257176_1.jpg
Bioactivity
 
Detects Recombinant Human CD20/MS4A1 Protein, N-His (Cat No.:TD-HY257011) in indirect ELISA.